Transcription of Hearts in Maine #140

Dr. Lisa:          This is Dr. Lisa Belisle and you’re listening to the Dr. Lisa Radio Hour and Podcast. Show #140 “Hearts in Maine” airing for the first time on Sunday, May 18, 2014. Hearth disease is the leading cause of death among American adults. Thus is generates much discussion in the fields of Medicine and Public Health. Today we speak with two physicians who have had many years of experience in cardiology yet continue to understand heart health in innovative ways. Join our conversations with Dr. Peter Shaw and Dr. Dervilla McCann and learn how our doctors are using their heads to gain important insights into Maine hearts. Thank you for joining us.

Any good doctor will tell you that the foundation of their own medical career is having good teachers, good Physician teachers, good other health care provider teachers and among my really basic foundational great teachers is Dr. Peter Shaw who actually is in the studio with us today. Dr. Peter Shaw is a Cardiologist in Portland at Martin’s Point Health Care. He’s been practicing medicine for 36 years and has been affiliated with Maine Medical Center and Mercy Hospital throughout his career in Portland. There’s really so much more behind that short bio but I just wanted to thank you for taking time out of your patient’s schedule and coming in and talking to us today.

Dr. Peter:        Thanks for asking me.

Dr. Lisa:          Dr. Shaw, it’s really interesting for me to have you here because it’s not just me that you have a relationship with. You’ve known my father as Dr. Charlie Belisle because you’ve been around the same length of time practicing medicine in the Portland area.

Dr. Peter:        I have, when I came here there were just a few of us cardiologist and several of us were covering each other at night and the large groups ultimately becoming the hospital owned practice evolved over many years. One of the great things about this city is the resources that it has and among those were the opportunities to practice and teach at two very great hospitals. Both of which had training programs that allowed me to do what I really have always felt my mission was and that is to take care of people and to pass on what I know to others. One of the important things about medicine I’ve always felt is good communication.

Communicating not only with your patients but also with other practitioners and also the public and communication is central to the fundamental meaning of Doctor which is a Latin word meaning teacher. I think that has been the principle by which I’ve lived and practiced and I’ve felt very gratified to be able to do that here.

Dr. Lisa:          When I was starting my medical training we were really right in the age of technology where it was about we were taught how to order test, we were taught how to make diagnosis based on testing. I know as a cardiologist you used test yourself but one of the things that I remember quite vividly was the time spent with you at the bed side of patients using one simple piece of equipment and that was the stethoscope. I remember it so clearly that you would first of all it would be important that the doctor-patient relationship was very strong and it was never assumed that this was okay and we’re just going to stick our stethoscope on you.

There was always that sense that it was important to bring that patient and as a teacher as well but then the learning of murmurs, the learning of abnormal pulse presentations, the physical diagnosis stuff which is something that I think it’s lost in today’s medicine. That was so strong in your teaching, is that something that you still count on, rely on yourself?

Dr. Peter:        Well, I don’t only count on it, I teach it. We have at Maine Medical Center a beautiful facility for teaching that scholars simulation center sponsored by Hannaford and it’s a state of the art structure that allows experience in the operating room and at the bed side doing instrumentation like Endoscopy. The bed side teaching which is I think irreplaceable has been greatly augmented by having idealized mechanical subjects that we can really demonstrate very clearly what particular feeling or sound or observation is. Then that could be taken by the interns and residents who are learning it to the bed side where they’re free to make observations on live patients.

One of the things that we try to do is get them to understand that they are not just listening at a patient’s heart but they are listening for a particular findings that will give them clues as to what diagnosis to then explore.

Dr. Lisa:          You have a background in public health, you spent two years at the Centers for Disease Control and not everybody would understand the length between Cardiology and Internal Medicine and Public Health. It’s pretty clear to you and I but tell us what it was about Public Health that caused you to go in that direction first.

Dr. Peter:        My first introduction to Public Health was actually in fourth year of Medical school and I was at the Columbia Medical School in New York. At least a third of our class went abroad for a couple of months to do Tropical Medicine, I did the last two months of Medical school in Liberia where it was a very different country at that point but where I was stationed at a place called [Zaza 00:08:26] which is up country several hours. My wife and I lived in a house there that was occupied by a nurse who had been there for probably 30 years and had made a huge impact bringing child birth from the jungle into the hospital. When we arrived at [Zaza 00:08:56] we arrived exactly at the same time as she died suddenly from Lassa fever which was epidemic disease at the time.

In the other half of the house where we’re living CDC had sent investigators to explore the reasons for this epidemic and to dissect animals and take samples. That really fascinated me even though I knew I wanted to be a Cardiologist I thought, “Hey, this is cool.” When I was given the opportunity to join the army in Vietnam I took even a better opportunity to go through the court program and to the CDC where I had seen this fascinating investigation go on. My area was believe it or not parasitic diseases and they still are important and as a matter of fact I probably knew more when I got to Maine about amoebiasis or malaria than anybody else.

It was really kind of side line but I didn’t I just concentrated on Cardiology. The CDC really opened my eyes to a number of things. First of all, I learned how to interpret and read journal articles and know what was believable and what perhaps was not. I learned more about biostatistics than I had learned in medical school until I learned about biostatistics in medical school. I have no memory of that at all but I certainly do at CDC and then that kept me aware of the larger picture so I just been very much aware that throughout my practice too as a matter of fact even though I was a Clinical Cardiologist and also I’m a faculty I helped to establish the Cardiac Rehabilitation program at the University of Southern Maine, it was called Lifeline.

Then in later years helped to establish Upbeat which was at Mercy and that ultimately transformed into turning point at Maine Medical Center which continues to be an extremely important not only personal health but public health facility. I think that that’s been a nice additional interest that I’ve pursued throughout my career.

Dr. Lisa:          You also took time not too long ago to go to Botswana where you thought that you’re going to be just doing standard Internal Medicine Primary Care but it turned out that you were able to marry your love of public health and your use of Echocardiograms or modern technology and your knowledge of infectious diseases and really provide some interesting, really learn some interesting things and provide some help.

Dr. Peter:        The University of Pennsylvania where I trained was inquiring among it’s trainees, former trainees anyone who could give time to their BUP that was the Botswana University of Pennsylvania partnership at diagnosing, treating and managing HIV aids and TV in Botswana. Additionally, Baylor has a similar program involving Pediatric patients and Harvard provided all the laboratory services there. I had a year of freedom so I signed up to go for three months and knowing what I did about Africa I inquired am I going to be involved just in teaching medical residence and house officers about how to be a doctor or how to treat HIV aids or is there any Cardiology there which I could actually help with.

I was told, “No, there’s not much Cardiology,” you can teach them how to be a doctor so knowing what I know about heart health in Africa I arranged with one of the Acrow Corporations to provide me a loaner Echocardiogram machine for three months. I spent time before I went learning how to do a study and then after I went the machine I’ve done time it was sent down from Nairobi to Gaborone which is the capital of Botswana where I was working. Within a day or two I was thinking of these unbelievable discoveries of Pathology that guided appropriate management. Anybody who appeared with swelling in their legs and troubled breathing was called CCF, Chronic Congestive Failure and everybody was treated the same but with the help of diagnostic skills that I had in the Echocardiogram to document what Pathology was there.

I was able to define how to refine the management of this patients to treat exactly what they had. Some had stiff hearts that were not dilated and swollen and unable to function properly. Others had huge fluid collections around the heart, something called the Pericardial effusion, some had severe valvular disease and in fact the TB, Aids population had frequent presentations with large Pericardial effusions and the echo machine helped me do guided Pericardiocentesis which is a technique by which a needle is placed into the chamber, into the space around the heart and the fluid is drained. I had to make my own equipment, I used intravenous catheter for the catheter to enter the space around the heart.

I used IV tubing to drain the fluid and I used the urine bag to collect the fluid in. It worked out beautifully. I did six of those while I was there, I found intracardiac tumors, I found two patients who had severe heart valve infections, the echo help me see how serious these were and lead to my sending them by plane to Johannesburg for heart surgery. They came back three weeks later with their intravenous catheters ready to get antibiotics for the next six weeks, new heart valves and feeling well again. That echo machine saved lives and it also made me able to be a much more effective practitioner and teacher.

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You also saw something that we see often in the United States which was hypertension but you saw some really severe and untreated hypertension which you showed me a picture of on your iPhone. I love this that you were able to show me pictures of CAT Scans and echo results on your iPhone. Why do you think that that is, that they aren’t able to treat something as basic as high blood pressure?

Dr. Peter:        Several reasons, I think number one it’s Africans and African Americans are very susceptible to hypertension and it’s prevalence is high. Second, the drug management of hypertension is not quite as persistent in a place like Southern Africa as it is in among a middle class population in United States. I think it’s certainly frequent in America that we’ve got populations that are no better served than people in rural Southern Africa and probably have the same incidents of complications of untreated disease. The most common cause is stroke in Southern Africa is really intricating hemorrhage and that’s usually hypertensive complication.

The last reason is also the inconsistency of drugs. People are treated with whatever drugs around for that few months and then when those drugs are used up then other drugs replace them and so trying to maintain a consistent in a hypertensive schedule is not that easy.

Dr. Lisa:          We actually have some similar problems even as you’ve said here in the United States where there is a segment of the population that doesn’t have access to medication. Not because it’s not right there and right available at their drug store but because they don’t have health insurance or they don’t have prescription coverage or they don’t have the funds to cover the co-payment. How does that feel to you that you can go from this country that’s underdeveloped to a country that is theoretically very well-developed and we still have some of the same issues?

Dr. Peter:        Well, I view medical care as a right, I view this whole question of why does America have 15 billion people without health insurance a moral issue. It’s not economic issue, it’s a moral issue. This is a horrible situation and I think there’s no excuse for it. I think that whatever we need to do in order to provide people the health care they need is essential and whether it’s through the affordable care act or whether it’s through a universal payment system or some way to provide health care to anyone who needs it is I think a responsibility of a society. I really feel it’s too bad and we got to do something to fix it.

Dr. Lisa:          It’s interesting to hear you say that because not all doctors are behind the affordable health care act for example, not all doctors are behind single pair systems or some of the legislation necessary. I would say that most doctors understand that there’s something about the system that’s not quite right.

Dr. Peter:        Absolutely, I think that the affordable care act is not perfect, it’s several thousand pages long because like every other legislation a lot of different interest groups need to be [assuaged 00:24:25] in order to reach consensus. In the case of providing health care, we live in America by health insurance, I think that it’s idealized if we could provide universal health care by single pair but on the other hand it’s just not the way America has worked. You can’t change this place in an instant. We have to work with what we have. I’m puzzled by the different messages I’m getting about the reasons to be concerned about Medicaid expansion. I recognize that Medicaid is not a panacea, it doesn’t pay very well.

It also is something that was a technique for trying to expand the number of people with some form of insurance. From the point of view of taking care of expanding medical expenses it will in itself cause issues of disagreement and discord. I think that there’s a lot of evolution that we have to undergo to bring medicine into the 21st century and beyond and to make it available to as many people as possible. I think we have to work together to determine what’s acceptable in the society and what’s not but in the end I think that since health care is right we have to find a way to provide it. It’s not just through free care, the hospital shouldn’t take the burden of that and it’s not through having different levels of quality of care. I think that that’s not acceptable either so there’s a lot of work to be done.

Dr. Lisa:          What I’m noticing about medicine is that there aren’t as many people who are staying in long enough to have a historical perspective about it. I mean I know I think about you, I think about my father who’s been practicing, I think he finished medical school in 1971. There are few other doctors who are of that ilk, who have been around long enough, I mean you’ve been practicing for 36 years.

Dr. Peter:        Yeah, I graduated in ’72.

Dr. Lisa:          How do we capture that historical perspective if there aren’t as many people who actually have been around long enough to have seen all of these shifts take place?

Dr. Peter:        There are a lot of people who’ve been around long enough to participate in that. For example, the Chief of Medicine at Penn, Arnold Relman. When I was in training, went on to other positions including being professor at Harvard and also editing The New England Journal. There are so many different things to do in medicine or around medicine just as you’re doing that if you’re awaken, alert and at all conscious of the evolution of society as well as medicine specifically. These awarenesses can happen, all I can say is that medicine is in constant evolution. I have changed how I practice basically every five years for my entire career and I’ve concentrated primarily on single laboratory entity that is Chief of Medicine at Penn, Arnold Ralman when I was in training went on to other positions including being professor at Harvard and also editing The New England Journal.

There are so many different things to do in medicine or around medicine just as you’re doing that if you’re awaken, alert and at all conscious of the evolution society as well as medicine specifically. These awarenesses can happen, all I can say is that medicine is in constant evolution. I have changed how I practice basically every five years for my entire career and I’ve concentrated primarily on single laboratory entity that is Echocardiography and always had that as ancillary to my practice as opposed to the thing I did. As echo has evolved and the treatment of patients has evolved and the management of illnesses evolved, it’s been like riding a surf board. It’s just been remarkable.

I can’t think of a better career for me and I think your example and your son who’s about to go into medicine I think that those who want to be doctors really find that this is a wonderful profession no matter what we’re paid. The fact that a number of the smartest graduates of [colleges 00:29:45] were going off in the money management instead of professions like medicine. You know what? They probably weren’t going to be in medicine for long anyway or doctors. I think that those who want to go into medicine are going to continue going into medicine and they are going to continue having experiences just like I’ve had for the last decades.

Dr. Lisa:          As you’ve mentioned, my son is thinking about going into medicine. Actually he’s applied to school and I think I’ve felt the same way that you’re describing. A lot of, I’ve talked a lot of doctors who had say, “I would never encourage my child to be a doctor,” I don’t feel that way. I think the important thing is you just know somewhat what you’re getting into right now and then realize that you’re probably going to have to have some nimbleness of intellect and emotion and some perseverance in order to just keep riding the wave as you’ve described. It’s a funny thing, if you’re going to medicine expecting one thing then probably it’s going to change by the time you graduate from medical school. Certainly in 35 years, 36 years it’s going to change. As long as you know.

Dr. Peter:        That’s right. All I can say is make sure that you get enough rest and enjoy what you’re doing, never stop learning and that will continue to be a fulfilling career.

Dr. Lisa:          Dr. Shaw, it’s been a pleasure to have you here today and I know with your very busy schedule we’re really privileged that you took the time to come in and talk with us. People who are interested in finding out more about your practice, they can go to the Martin’s Point Health Care website and I appreciate all that you’ve done and thank you for making me a better doctor. I got a new stethoscope recently and I thought Dr. Shaw would really like this stethoscope. You’ve made a big difference in my life and I’m sure you’ve made the same big difference in the lives of medical students and residents around the state.

Dr. Peter:        Well, thank you Lisa. I will say that as long as I’ve been in practicing I’d still needed to buy a new stethoscope which I am about to receive in the mail this week. It’s an ongoing process and I think it’s been a thrilling career.

Dr. Lisa:          We’ve been speaking with Dr. Peter Shaw who’s a Cardiologist with Martin’s Point Health Care and keep doing the good work.

Dr. Peter:        Thank you.

Dr. Lisa:          As a physician and a small business owner, I rely on Marci Booth from Booth Maine to help me with my own business and to help me live my own life fully. Here are few thoughts from Marci.

Marci:             When I consider today’s show topic I can’t help but equate it with what happens in my business. I have to remind myself and my team to consider how what we do for our clients helps their businesses stay healthy. We are often there to diagnose problems and prescribe solutions that ease business aches and pains. We have to do it with empathy, compassion and heart and when we see results and our clients are happy and successful, that gives us the deepest sense of satisfaction and gratitude. I’m Marci Booth, let’s talk about the changes you need, boothmaine.com.

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Dr. Lisa:          We all know that Maine is a small state and especially when it comes to things like public health. I was privileged to work with Dr. Dervilla McCann on a public health project through Maine Health several years ago and today we have her with us again. Dr. McCann is formerly the Director of the Cardiology Division at Saint Mary’s Regional Medical Center and is on the medical staff and is a full-time Cardiologist with Central Maine Medical Center in Lewiston. Thanks for coming in.

Dr. McCann:   Thank you for having me, Lisa.

Dr. Lisa:          Dr. McCann, you have a very interesting background, you spent sometime out of the state before you chose to come to Maine. Tell me a little bit about what brought you here and your background.

Dr. McCann:   My first real full-time exposure to Maine was when I came here as a freshman at Bates College and I fell in love with the state at that time. I left after graduation but I had planted a little seed, I talked my parents into moving to Portland. They moved while I was still in college and I left went to medical school, joined the Navy, I got married and came back eventually to the state in ’96. Drawn both by the fact that my parents were still here and I wanted my kids to get to know them a little bit. I had a job so that was another pull but basically I’d always love to stay and had always been looking for way to get back here.

Dr. Lisa:          Your family is originally from?

Dr. McCann:   Ireland. My parents are both Irish. They met in medical school and immigrated initially to Newfoundland, Canada and then over to New England and eventually settling in Portland.

Dr. Lisa:          What type of physicians are they?

Dr. McCann:   Both of my parents are physiatrist which is specialty focused on rehabilitation medicine. My dad was really one of the founding members of the Wheelchair Sports Association and was a real pioneer as was my mom. Really they both were very interested in sports for the disabled and were part of that early movement and have remained very active in that element of sports ever since they started.

Dr. Lisa:          Was the fact that your parents were Physicians and basically what is a public health related field that influenced your decision to go into?

Dr. McCann:   I think I decided to be a doctor when I was about seven and I really feel that you select your profession in part because you’re selecting a peer group. You want to continue to grow intellectually, you want to be challenged and you want to help people. Medicine was a really great way to do that. I was an internist for a number of years but I found that my personality really match better with cardiology. There was pretty immediate return, an intervention with cardiology. Of course when I became a cardiologist, cardiac catheterization was relatively new and intervention was in its infancy. Many technologies have advanced dramatically since I started, it’s been really challenging to stay current and to stay as well-informed as you can be for your patients but that’s part of the beauty of it I suppose.

Dr. Lisa:          Do you ever speak with your parents about the Irish medical school system or the Irish medical system and how it differs from the American system and where we are today?

Dr. McCann:   Yeah, we talk about it a lot especially at the beginning of my American medical training and actually I went to Ireland to experience it with my husband. I was married at the time and we did a rotation in Dublin. That was really an interesting experience, the focus was quite different, the Irish medical students relied far less on labs and technology. They really focused on physical diagnosis and the history, the bed side examination. I couldn’t believe the stuff they memorize, it was really impressive, very, very bright. Also, when I was there and this was years ago but the medical system was also very informed by religion, you know Catholic Ireland.

There were some social differences that we observe, my husband and I observed when we were there regarding the communication with the patient, the communication with the family. It was a really good thing to experience and see up close and personally so that I understood much better how my parents have been trained and what their focus had been.

Dr. Lisa:          Why did you chose to go into the Navy and how did that shaped your actual?

Dr. McCann:   Money. Had none, was married, wanted to be independent, seemed like a good idea at the time, the uniforms were definitely up pull because they look great. Seriously, medical school at the time that I entered, it was during the Reagan administration. I went to Tufts, the tuition doubled the year before I got there because Federal subsidies were removed. Private medical schools around the country were suddenly seeing a very dramatic acceleration in cost. My husband and I both had to find a way to get through this and so we applied for a Navy scholarship. He got his the very first year, I got mine our second year. I worked as an Audio-Visual Tech during my whole first year of medical school to pay the bills.

I have no regrets about this at all, it really turned out to be a fantastic experience, a great adventure and believe it or not it turns out that after Tufts medical school I applied to Bellevue Hospital and was accepted there for my residency at the height of the aids epidemic. We had no idea what was in store for us during those three very difficult years. 50% of my patients had aids or aids related illness and 50% of the ones with aids died while I was caring for them. It was inundation with one type of disease and it was a very sad time with very little that I could do. After I got done with my residency, that was the time that I started my Navy payback and I learned more internal medicine in the Navy because they specifically excluded HIV positivity.

It was really helpful for me to have had those two experiences. One, very much based in a public health crisis with intensive care medicine emphasis and very poor outcomes so I became really, I really understood the critical care elements of medical care. The navy taught me a completely different side the outpatient side, taking care of people who are essentially well but who have chronic medical problems as they age so it was really terrific double teaching track so to speak.

Dr. Lisa:          You’ve had to be somewhat nimble as you’ve gone through because you’ve dealt with different demographic groups, you’ve been to different places and now you find yourself in Lewiston and you have this interest in what’s going on with the Franco-American, the French-Canadian formerly French-Canadian population. Tell me about that.

Dr. McCann:   Well, there’s no question, my life has zigged and zagged. I have not been sort of the shooting star with a linear arch, that has not happened but that’s the great thing about America I suppose and about the opportunities that we can all take if we want to. I’ve been exposed to a lot of different ethnic groups on the West coast. I met a lot of Pacific Islanders in the Navy, I met a number of Cuban refugees. In Boston, I’ve met the Irish-Americans that certainly informed my understanding of that group but definitely in Lewiston we have a high population of Franco-Americans, I believe it’s 29% of the city which is more than the state as a whole and the state has a very high percentage of Franco-Americans.

That is fine with me, I find my patients of Franco descent particularly the ones who speak French as a first language to be really interesting and wonderful group of people to take care of. I really enjoyed them, I can remember and I speak a little bit of French which is helpful when you go to for example the emergency room sometimes especially at the beginning when I first got there I can recall the French speaking nuns would be behind the curtains speaking French to the patients. It was almost, that was a lovely thing spiritual thing. That continuous to inform the community although loses, rapidly changing and becoming far more cosmopolitan. Unfortunately that French culture is not completely sustainable although some wonderful leaders in the community are really trying to hang on to the history and the culture and the language.

Dr. Lisa:          As you’ve been taking care of this particular population, you’ve noticed some things about medically that have been noticed before but they just caught your interest as a Cardiologist.

Dr. McCann:   When I first arrived in Lewiston and started seeing really young people with heart attacks it was a bit of a surprise. Often these folks, young heart attack victims would often have whole lot of risk factors, they would have diabetes or they would smoke or they would have high cholesterol or high blood pressure, you know many different risk factors. What I kept finding was very young people with very high cholesterols and I started looking into the sub type of patient, people with familial hypercholesterolemia. When you look at cholesterol, we divide it up into sub groups and there’s this one genetic tendency that gives people very high LDL cholesterols, that’s the bad … What we used to call the bad cholesterol.

Individuals with familial hypercholesterolemia inherit this from their parents, if they get both genes one from the dad, one from the mom they are called homozygotes and those types are very sick at a very early age. They typically have strokes or heart attacks sometimes in their teens and they often don’t survive pass the age of 30. If you get just one copy of the gene from either one of your parents, you’re called a heterozygote. Heterozygotes do have very high LDL cholesterols but they are less likely to have that very early childhood form of heart disease but they succumb to coronary artery problems, that’s arteries of the heart in their 30’s and 40’s, much, much earlier than normal.

Dr. Lisa:          The goal of the Dr. Lisa Radio Hour is to help make connections between the health of the individual and the health of the community. The goal of Ted Carter Inspired Landscapes is to deepen our appreciation for the natural world. Here to speak with us today is Ted Carter.

Ted:                Some mornings I lie in bed exhausted thinking, “Wow, did I really signed up for all this?” I think we’ve all been there where life just is a struggle sometimes and it’s long, it’s hard, it’s arduous. I also think that that’s how the human spirit is tested and I think that sometimes when we’re pushed up against the wall that’s when our best forms of creation come out. In looking back at the most difficult projects I have been on, something came out of those projects that wouldn’t have otherwise come out if it was easy I guess you might say. I think in reflecting back on life in general we look at life and we say, “You know, those were really difficult times but I got through it and I got to the other side and I was able to create something that was really meaningful.

It even has greater meaning and depth because of the struggle.” I guess we have to say in life we have to bless our struggles and bless the journey and make the most of everything we have and be grateful for it. I’m Ted Carter and if you’d like to contact me I can be reached at tedcarterdesign.com.

Dr. Lisa:          The Dr. Lisa Radio Hour and Podcast understands the importance of the health of the body, mind and spirit. Here to talk about the health of the body is Jim Greatorex of Premier Sports Health, a division of Black Bear Medical.

Jim:                 At Black Bear Medical, we lead with our hearts everyday. From our daily fund raisers for the numerous charities in Maine to our everyday customer service. We do what we can do to help our customers feel better from the inside out. Injuries and ailments can be scary and have just as much of an emotional impact as a physical one. Let our experts look at the whole you and your situation and help suggest the products and services you need to get you back to being you. It’s part of our culture and our promise to you. Visit blackbearmedical.com or stop by one of our retail stores in Portland or Bangor to see just how much heart we have.

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Dr. Lisa:          You wanted to learn more about why this was happening?

Dr. McCann:   Exactly.

Dr. Lisa:          Having taken a very, I guess we’ll call it holistic and family based approach to the way that you practice medicine. You started digging into the history of this group.

Dr. McCann:   Right. It turns out that familial hypercholesterolemia is a gene that’s seen ubiquitously, it’s all over the world. Every group, every country, every ethnic group has some expression of this gene. There are sub groups, sub populations that seemed to have a higher risk and the Franco-American population is one such. This appears to be secondary to what we call the founder effect and this is where the story got very interesting for me. It turns out that there were probably four to six founding families from France who went to Quebec and became the early settlers of that area really founding Quebec and because of language, culture, religion they intermarried and it turns out historically apparently the French government gave them subsidies and additional moneys if they reproduced and had a lots of kids.

This founding families appeared to have carried the gene with them and appeared to be the source for this higher than usual expression of this gene in this population. Now, go to the industrial revolution with mills being built around New England area and a rail road that went directly from Quebec to Portland. The people of Lewiston built a rail road spur so people could get on the train in Quebec and get on and make it changing, get off in Lewiston and thousands of Franco-Americans ended up coming to Lewiston to work in the mills where they were able to make a much better living.

They’re then as subsistence farmers in Quebec but the same culture, the same language, the same shared heritage tended to create a situation where people continue to intermarry and they had lots and lots of kids. The end result of this is the gene became concentrated and amplified in this particular population. If you claim Franco-American descent you are more likely than the average person to carry the gene for familial hypercholesterolemia.

Dr. Lisa:          What does this mean for you as a Cardiologist? Cholesterol is still confusing us. I mean I’m a primary care doctor and we’re uncertain as to how we’re supposed to deal with this but we know that there is a problem with cholesterol and the heart. How does this change the way that you work within your practice?

Dr. McCann:   You’re absolutely right, cholesterol is confusing. Believe it or not it’s still confusing to Cardiologist too. We just received some new guidelines last November, the American Heart Association, American College of Cardiology published some new guidelines that had been quite controversial actually. One thing that has continued to be the mantra is that LDL cholesterols that are really high need to be very aggressively treated. Unfortunately, patients with familial hypercholesterolemia have LDL cholesterols, we like to see them under a 100. Their LDL cholesterols are typically 190 or greater so they are really very, very high.

Lifestyle modification remains the main stay of therapy for cholesterol treatment and that means smoking cessation, exercise, achievement of your ideal body weight and healthy diet which is not high in trans fats or hopefully is very balanced with lots of fruits, vegetables, whole grains. I often will talk about the Mediterranean diet to my patients which really has some good evidence behind it as a very healthy way to eat. With familial hypercholesterolemia, even aggressive life style modification typically isn’t enough and so we have to treat these people with some pharmacologic agent. The one that seems to be coming after all these years and lots of other tries, with lots of different things, statin therapy appears to be the safest and most effective therapy for them.

In fact, it can really do wonders for these patients and markedly reduce the risk of heart disease. We frequently as Physicians work in silos and we have not got strong links to community programs for dietary modifications, smoking cessation, exercise, those are all different packets of talent that are scattered around our communities. We’re very busy, we’re all under a lot of pressure to just get through the patients of the day. With the support of Central Maine Medical Center and St. Mary’s, I’ve been working with both hospitals in Lewiston because we’ve recognized that this is a community problem. We are working now on a pilot project to link all of those things, to make sure that when we identify high risk patients we do a couple of things.

We sit down and talk with them, explain the genetics and try to screen their first degree relatives, that’s called cascade screening. It’s very cost effective and were very likely to identify other individuals who are high risk using that approach. Just mother, father, brother, sisters and kids. If we screen them, we’re likely to find additional family members with high cholesterol. Then we really work on the lifestyle stuff, give them the support that they need to quit smoking if they smoke, diet is focused on healthy diet, we’ve gotten some support from St. Mary’s Nutrition Center. We think we’re going to be using them as part of our process to educate and we got all sorts of exercise, groups in the area that would like to be part of this and we’re going to try to create links for our patients.

We’re going to try to maintain the primary care provider as the central link and the central connection for that patient. We are going to be in the background trying to add quality to what the primary care provider is going to provide but this program today is very helpful because I want to make sure that we get the word out to the public not just to the medical community but to the public that this is a unique not isolated to Franco-Americans but particularly important to Franco-Americans in the state of Maine. The real reason I got started on all this is we got this brand new electronic medical record and you can do all sorts of fun things with it like ask it questions.

I asked the question, how many patients do we have on our system and the answer is 80,000. How many of them have ever had an LDL cholesterol of greater than 190 and that’s a standard starting point to identify individuals with familial hypercholesterolemia. Within a population of 80,000 you would anticipate about a 160 patients, that’s 0.02%. That is one in 500 people are typically expected to have this gene. We got 4,000 patients, my jaw dropped when I saw that number. That was really the impetus behind all of the activity that we’ve been engaging in over the last several months.

Dr. Lisa:          Can people contact you through the Central Maine Medical Center website or switch board?

Dr. McCann:   They absolutely can and I would encourage them to keep an eye out because we are going to try to spread the word both publicly. They don’t have to come to me personally, they can continue to work with their primary care providers, their primary care providers. We’ll be probably publishing our results I intend to try to perhaps get together a brochure to help patients educate themselves about what they need to do. I would love to get some money to distribute that, anybody out there who’d like to give me some money to get this really jump started that will be great, thanks in advance. We’re starting small, we’re going to do pilot, we’re going to build and hopefully we’ll grow it.

Dr. Lisa:          Thank you for the work that you continue to do for patients in Lewiston area and the state of Maine and thank you for really making an effort to embrace medicine where it is right now. Because it is an exciting time to be in medicine and there are a lot of things we can offer patients now that we weren’t able to offer them 10, 15 years ago before the age of electronic medical records. We’ve been speaking with Dr. Dervilla McCann who’s a Cardiologist with Central Maine Medical Center in Lewiston. Thanks for coming in.

Dr. McCann:   Thanks so much for having me Lisa, I really appreciate you giving me this time.

Dr. Lisa:          You’ve been listening to the Dr. Lisa Radio Hour and Podcast show number 140. Hearts in Maine. Our guest have included Dr. Peter Shaw and Dr. Dervilla McCann. For more information on our guests and extended interviews visit doctorlisa.org. The Dr. Lisa Radio Hour and Podcast is downloadable for free on iTunes. For preview of each week show, sign up for our enewsletter and like our Dr. Lisa Facebook page. Follow me on Twitter and as Bountiful One on Instagram. We love to hear from you so please let us know what you think of the Dr. Lisa Radio Hour. We welcome your suggestions for future shows.

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